Diclofenac works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) which are responsible for the production of prostaglandins—chemicals that trigger pain and inflammation. When applied to the skin, the medication is absorbed and targets the painful area directly, making it a localized and safer approach for many individuals. https://medicoiq.com/what-is-diclofenac-sodium-topical-gel-used-for/